Milan Analytica AG

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Neurodegeneration, tumor biomarkers, formalin-fixed paraffin-embedded (FFPE) staining

Ladies and Gentlemen

The “histonova” antibodies for human pathology are paraffin penetrating antibodies for excellent colouring results.
These paraffin-penetrating antibodies are especially designed for high reproducibility and reliability.

I. Neurodegeneration

We would like to present to you antibodies against biomarkers for Alzheimer’s and Parkinson’s disease, Creutzfeld-Jakob disease, bovine spongiform encephalopathy, Scrapie, chronic wasting disease etc.
Please find under the following link different monoclonal antibodies and ELISA kits from Dianova for the determination of biomarkers like Tau, Prion protein (PrPSc), alpha-Synuclein and so on.

For more information please klick here.

Neurodegeneration_disease   Parkinsons_disease

Alzheimer´s disease: Amyloid beta peptide accumulates in the neutral endoplasmatic reticulum and extracellulary as plaques


Parkinson´s disease: Lewy body
dementia: soluble monomers of
Alpha-Synuclein are converted into
insoluble aggregates forming the
Lewy bodies and Lewy neurites

II. Staining of formalin-fixed paraffin-embedded (FFPE) tissue sections

  • anti-PD-1 (Programmed cell death 1; marker for T-cell lymphomata)
  • anti-TdT (anti-terminal deoxynucleotidy transferase; marker for precursor B- and T-cells)
  • anti-Ki-67 (Ki originally standing for the german city Kiel; marker for cell proliferation)
  • anti-p53 (protein 53, tumor suppressor; marker for malignant transformation)
  • anti-CEA (carcinoembryonic antigen; marker for most carcinomata (epithelial tumors)
  • anti-EpCAM (Epithelial cell adhesion molecule; marker for epithelial tumor cells)
  • anti-CD30 (marker for lymphomata)
  • anti-IDH1 (Isocitrate dehydrogenase; marker for astrocytomata and oligodendrogliomata)

For preclinical research:

  • Rat anti-mouse CD31 (This is the first antibody which allows the detection of the endothelial cell marker CD31 in standard formalin-fixed paraffin-embedded tissue sections from mice.)


Immunostaining of a colon carcinoma with anti-CEA


GFAP / IDH1 R132H double staining of an oligodendroglioma tumor margin

For more information please klick here.

MILAN Analytica is the exclusive distributor for histonova products in Switzerland.
We would be glad to provide you with further information on the histonova products from Dianova.
Please do not hesitate to contact us!

Thank you for your attention and best regards

Andy Uhlig
Marketing and Sales Manager Distribution

Baslerstrasse 15
4310 Rheinfelden

fon +41 (0)61 845 99 88
fax +41 (0)61 845 99 87

MILAN ANALYTICA AG • 4310 Rheinfelden • Switzerland • phone 061 845 99 88
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