Milan Analytica AG

 
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Ladies and gentlemen,

Get the best for your FFPE staining!

Dianova product list

Use this link to visit the product lists from Dianova

 

 

New Ki-67 antibody

 

New p53 antibody

 

 

 
The antigen Ki-67, identified by the monoclonal antibody Ki-67, is a nuclear protein associated with ribosomal RNA transcription and cellular proliferation.
MILAN Analytica AG is offering a new Ki-67 antibody (clone Ki-67P) from Dianova with superior staining quality:

High titer
Specificity: Human Ki-67/MIB1
Clone: Ki-67P
Host/Isotype: Mouse/IgG1
Application: IHC-FFPE (immunohistochemistry with formalin fixated paraffin embedded tissue sections)
Dilution: 1:100-1:200

 

p53 is a tumor suppressor protein preventing genome mutation. MILAN Analytica AG is offering a new p53 antibody (clone CC53) from Dianova with superior staining quality:



High titer
Specificity Human: p53
Clone: CC53
Host/Isotype: Mouse/IgG1
Application: IHC-FFPE (immunohistochemistry with formalin fixated paraffin embedded tissue sections)
Dilution 1:100-1:200

 

New Ki-67 and p53 antibody

 

New Ki-67 and p53 antibody
Immunostaining with clone Ki-67P. Cervix uteri. The normal cervix epithelium is Ki-67 negative in contrast to the areas with a CIN II and CIN II-III (CIN cervical intraepithelial neoplasia)

 

Immunostaining with clone CC53. Squamous cell carcinoma of the neck. Nearly all tumor cells are strongly positive in their nuclei. This p53 upregulation points to a loss of its tumor suppressor function which permits the survival of cells with oncogenic genetic alterations

 

New Ki-67 and p53 antibody

 

New Ki-67 and p53 antibody
Squamous cell carcinoma of the neck. Nearly all of the tumor cells are in proliferation, showing that the carcinoma is rapidly growing

 

Immunostaining with clone CC53. Colon carcinoma. Nearly all tumor cells are strongly p53 positive in their nuclei. This p53 upregulation points to a loss of its tumor suppressor function which permits the survival of cells with oncogenic genetic alterations

 

New Ki-67 and p53 antibody

 

New Ki-67 and p53 antibody
Colon carcinoma. Most of the tumor cells are proliferating, indicating a fast growing carcinoma

 

Immunostaining with clone CC53. Chronic lymphocytic leukemia (CLL) transformed into a diffuse large B-cell lymphoma (DLBCL) = Richter syndrom. The non-transformed CLL area is p53 negative whereas most of the transformed DLBCL cells are strongly p53 positve. This p53 upregulation suggests that the transformation is associated with a loss of the TP53 tumor suppressor function which permits the survival of cells with oncogenic genetic alterations.

Please do not hesitate to contact us for further information.

Thank you for your attention and best regards

Andy Uhlig
Marketing and Sales Manager Distribution

 

MILAN ANALYTICA AG
Baslerstrasse 15
4310 Rheinfelden/Basel
Switzerland

fon +41 (0)61 845 99 88
fax +41 (0)61 845 99 87
e-mail: andy.uhlig@milananalytica.ch
www.milananalytica.ch

MILAN ANALYTICA AG • 4310 Rheinfelden • Switzerland • phone 0041 61 845 99 88
If you do not want to receive such information, please send an e-mail to response@milananalytica.ch